ZNF773

Across TCGA pan-cancer cohorts, ZNF773 Mutation is linked to patient survival in 6 of 34 cancer types, making it a survival-associated ZNF773 data layer compared with 22 for mass-spec protein.

The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ZNF773 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF773 expression acts as an unfavorable survival marker.

BRCA, KICH, and DLBC are the cancer types where ZNF773 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BRCA	OS	Median	II,III,IV	0.570	0.913	<.001	38	view →
KICH	DFS	Median	All	0.102	0.848	.004	13	view →
DLBC	OS	Median	All	0.054	0.842	<.001	12	view →
SKCM	OS	Median	III,IV	0.179	0.721	<.001	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
BLCA	DFS	Median	IV	0.146	0.471	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

ZNF773–BRCA (OS)

Open the BRCA breakdown →