ZNF773

Across TCGA patient cohorts, ZNF773 mutation is significantly associated with the RNA expression of many other genes, with 1,176 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF773-associated genes across cancer lineages are TICRR, RAD51, and MIR495. Each is linked with ZNF773 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF773-to-partner and partner-to-ZNF773 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TICRR grouped by ZNF773-low versus ZNF773-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF773→partner) and Y-score (partner→ZNF773) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TICRR →	+0.783	+3.472	<.001	.002	3	3
UCEC	RAD51 →	+0.739	+2.513	<.001	.001	3	3
SKCM	MIR495 →	+0.184	+4.634	<.001	.003	3	3
UCEC	MND1 →	+0.689	+3.375	.004	.004	3	3
LUAD	RNU4-56P →	+0.182	+4.155	<.001	.007	3	3
UCEC	SKA1 →	+0.701	+2.513	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,176 associations by consensus.

TICRR by ZNF773 expression — COAD

Explore this box plot interactively →