ZNF773

Across TCGA patient cohorts, ZNF773 mutation is significantly associated with the total protein of many other genes, with 36 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF773-associated genes across cancer lineages are Caspase-7-cleavedD198, INPP4B, and Notch1. Each is linked with ZNF773 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF773-to-partner and partner-to-ZNF773 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by ZNF773-low versus ZNF773-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF773→partner) and Y-score (partner→ZNF773) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.968	+2.824	.006	.034	3	3
UCEC	INPP4B →	-0.302	-2.102	.032	.019	3	2
UCEC	Notch1 →	+0.206	+3.331	<.001	.005	3	2
UCEC	4E-BP1 →	+0.475	+3.489	<.001	.002	2	3
UCEC	C-Raf →	+0.223	+2.584	<.001	.010	3	2
COAD	FASN →	+0.530	+2.330	.002	.020	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Caspase-7-cleavedD198 by ZNF773 expression — COAD

Explore this box plot interactively →