ZNF773

Across TCGA cell cohorts, ZNF773 mutation is significantly associated with the drug of many other genes, with 26 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF773-associated genes across cancer lineages are EHT-1864, PRT062607, and Quizartinib. Each is linked with ZNF773 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF773-to-partner and partner-to-ZNF773 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EHT-1864 grouped by ZNF773-low versus ZNF773-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF773→partner) and Y-score (partner→ZNF773) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	EHT-1864 →	+0.335	+2.678	.049	.037	3	1
LARGE_INTESTINE	PRT062607 →	+0.534	+2.769	.034	.040	3	1
LARGE_INTESTINE	Quizartinib →	+0.370	+2.652	.021	.045	3	1
LARGE_INTESTINE	SU11274 →	+0.424	+2.652	.042	.045	3	1
LARGE_INTESTINE	AZD5438 →	+0.522	+2.777	.034	.038	2	1
LARGE_INTESTINE	Leflunomide →	+0.274	+2.769	.032	.040	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 26 associations by consensus.

EHT-1864 by ZNF773 expression — LARGE_INTESTINE

Explore this box plot interactively →