ZNF771

Across TCGA pan-cancer cohorts, ZNF771 RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of ZNF771’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ZNF771 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types ZNF771 is over-expressed in tumor, although a few such as KICH and UCEC show the opposite, repressed pattern.

KIRP, LIHC, and KICH are the cancer types where ZNF771 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ZNF771 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Female	All	+0.915	<.001	11	view →
LIHC	Female	All	+0.714	<.001	9	view →
KICH	Female	II,III,IV	−0.865	<.001	8	view →
HNSC	Male	III,IV	+0.718	<.001	8	view →
LUAD	Male	All	+0.395	<.001	8	view →
LUSC	Female	All	+0.710	<.001	6	view →
UCEC	All	All	−0.506	.005	6	view →
BRCA	Female	All	+0.256	<.001	6	view →
COAD	Female	II,III,IV	+0.765	<.001	4	view →
CHOL	All	All	+0.656	<.001	3	view →
BLCA	All	IV	−0.964	.006	2	view →
ESCA	All	II,III,IV	+0.554	.024	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

ZNF771–KIRP

Open the KIRP breakdown →