Across TCGA patient cohorts, ZNF770 protein abundance is significantly associated with the RNA expression of many other genes, with 562 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF770-associated genes across cancer lineages are RAB23, ARHGAP40, and PROZ. Each is linked with ZNF770 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF770-to-partner and partner-to-ZNF770 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF770→partner) and Y-score (partner→ZNF770) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	RAB23 →	-0.797	-0.876	.007	.007	3	1
HNSC	ARHGAP40 →	+1.376	+0.556	<.001	.004	3	1
HNSC	PROZ →	+0.658	+0.578	.001	.005	3	1
HNSC	GRP →	-1.744	-0.579	<.001	<.001	3	1
HNSC	SKIL →	-0.788	-0.415	.003	.001	3	1
HNSC	ITGAV →	-0.824	-0.485	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 562 associations by consensus.

Exploration

ZNF770 survival (RNA) · tumor vs normal (RNA) · all ZNF770 data types