Across TCGA patient cohorts, ZNF770 mutation is significantly associated with the RNA expression of many other genes, with 3,859 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF770-associated genes across cancer lineages are RNA5SP65, CST8, and MIR549A. Each is linked with ZNF770 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF770-to-partner and partner-to-ZNF770 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF770→partner) and Y-score (partner→ZNF770) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNA5SP65 →	+0.264	+4.867	<.001	.005	3	3
CESC	CST8 →	+0.414	+3.402	<.001	.009	3	2
CESC	MIR549A →	+0.186	+4.020	<.001	.009	3	2
LUAD	H2BC1 →	+0.561	+4.257	.004	<.001	3	2
LUAD	YWHAZP8 →	+0.053	+3.928	<.001	.002	3	2
LUAD	RPS20P13 →	+0.595	+4.178	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,859 associations by consensus.

Exploration

ZNF770 survival (RNA) · tumor vs normal (RNA) · all ZNF770 data types