Across TCGA cell cohorts, ZNF770 mutation is significantly associated with the RNA expression of many other genes, with 66 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZNF770-associated genes across cancer lineages are BTNL2, KRTAP4-4, and MROH2B. Each is linked with ZNF770 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF770-to-partner and partner-to-ZNF770 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF770→partner) and Y-score (partner→ZNF770) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	BTNL2 →	+0.079	+4.209	<.001	.006	3	2
BLOOD_Lymphoma	KRTAP4-4 →	+0.019	+4.058	<.001	.009	3	2
BLOOD_Lymphoma	MROH2B →	+0.050	+4.058	<.001	.009	3	2
SKIN	OR6N1 →	+0.271	+5.415	<.001	.004	3	2
PANCREAS	BPIFB6 →	+0.086	+5.000	<.001	.006	3	1
PANCREAS	MTRNR2L5 →	+0.026	+5.614	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 66 associations by consensus.

Exploration

ZNF770 survival (RNA) · tumor vs normal (RNA) · all ZNF770 data types