ZNF768

Across TCGA patient cohorts, ZNF768 mutation is significantly associated with the RNA expression of many other genes, with 896 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF768-associated genes across cancer lineages are MICU1, RNU6-1246P, and RNU6-39P. Each is linked with ZNF768 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF768-to-partner and partner-to-ZNF768 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MICU1 grouped by ZNF768-low versus ZNF768-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF768→partner) and Y-score (partner→ZNF768) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	MICU1 →	+0.402	+2.604	.005	.005	3	3
LUSC	RNU6-1246P →	+0.505	+4.736	<.001	.001	3	3
BLCA	RNU6-39P →	+0.286	+3.527	.001	.007	3	2
HNSC	SNORD114-28 →	+0.471	+4.505	<.001	.009	3	2
HNSC	RNY3P11 →	+0.373	+4.505	<.001	.009	3	2
HNSC	SNORA48B →	+0.200	+4.655	.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 896 associations by consensus.

MICU1 by ZNF768 expression — SKCM

Explore this box plot interactively →