ZNF768

Across TCGA cell cohorts, ZNF768 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,378 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ZNF768-associated GO terms across cancer lineages are Regulation of chromatin organization, Positive regulation of intracellular steroid hormone receptor signaling pathway, and Negative regulation of syncytium formation by plasma membrane fusion. Each is linked with ZNF768 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZNF768-to-partner and partner-to-ZNF768 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of chromatin organization grouped by ZNF768-low versus ZNF768-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF768→partner) and Y-score (partner→ZNF768) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of chromatin organization →	+0.125	+0.631	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.115	+0.515	<.001	<.001	3	13
STOMACH	Negative regulation of syncytium formation by plasma membrane fusion →	+0.136	+0.617	<.001	<.001	3	11
STOMACH	Transcription initiation-coupled chromatin remodeling →	+0.110	+0.894	<.001	<.001	3	11
LUNG_SCLC	Positive regulation of proteasomal ubiquitin-dependent protein catabolic process →	+0.069	+0.482	<.001	<.001	3	11
KIDNEY	Regulation of macrophage proliferation →	+0.224	+0.726	<.001	.002	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,378 associations by consensus.

Regulation of chromatin organization by ZNF768 expression — LUNG_SCLC

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