ZNF768

Across TCGA cell cohorts, ZNF768 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF768-associated genes across cancer lineages are PRR23A, INSL5, and NEUROD6. Each is linked with ZNF768 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF768-to-partner and partner-to-ZNF768 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23A grouped by ZNF768-low versus ZNF768-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF768→partner) and Y-score (partner→ZNF768) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRR23A →	+0.040	+4.217	<.001	.001	3	2
BLOOD_Leukemia	INSL5 →	+0.040	+2.661	<.001	.005	3	2
URINARY_TRACT	NEUROD6 →	+0.030	+5.087	<.001	.004	3	1
URINARY_TRACT	SKOR2 →	+0.050	+5.087	<.001	.004	3	1
LARGE_INTESTINE	BPIFB6 →	+0.020	+4.437	<.001	.004	3	1
LARGE_INTESTINE	HTR1E →	+0.048	+3.930	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

PRR23A by ZNF768 expression — LARGE_INTESTINE

Explore this box plot interactively →