Across TCGA patient cohorts, ZNF766 mutation is significantly associated with the total protein of many other genes, with 31 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF766-associated genes across cancer lineages are Notch1, PCNA, and eIF4E. Each is linked with ZNF766 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF766-to-partner and partner-to-ZNF766 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF766→partner) and Y-score (partner→ZNF766) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Notch1 →	+0.170	+1.584	<.001	.005	3	2
UCEC	PCNA →	+0.179	+2.247	.008	.001	3	2
UCEC	eIF4E →	+0.148	+2.013	.026	.016	3	1
UCEC	A-Raf_pS299 →	-0.108	-1.678	.004	.021	3	1
UCEC	FoxM1 →	+0.174	+1.353	.033	.015	3	1
UCEC	FOXO3a_pS318_S321 →	-0.088	-1.405	.025	.043	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 31 associations by consensus.

Exploration

ZNF766 survival (RNA) · tumor vs normal (RNA) · all ZNF766 data types