Across TCGA cell cohorts, ZNF766 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. UPPER_AERODIGESTIVE_TRACT shows the largest number of these associations.

The most reproducible ZNF766-associated genes across cancer lineages are GALP, BMP10, and OR2AP1. Each is linked with ZNF766 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF766-to-partner and partner-to-ZNF766 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF766→partner) and Y-score (partner→ZNF766) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	GALP →	+0.610	+5.357	<.001	.003	3	2
LUNG_NSCLC_LUAD	BMP10 →	+0.018	+4.212	<.001	.007	3	1
LUNG_NSCLC_LUAD	OR2AP1 →	+0.012	+4.662	<.001	.005	3	1
LUNG_NSCLC_LUAD	C7orf77 →	+0.046	+4.662	<.001	.005	3	1
UPPER_AERODIGESTIVE_TRACT	TNP2 →	+0.031	+4.736	<.001	.009	3	1
UPPER_AERODIGESTIVE_TRACT	RESP18 →	+0.040	+5.357	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

ZNF766 survival (RNA) · tumor vs normal (RNA) · all ZNF766 data types