ZNF764

Across TCGA cell cohorts, ZNF764 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,658 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF764-associated GO terms across cancer lineages are Positive regulation of intracellular steroid hormone receptor signaling pathway, Positive regulation of intracellular estrogen receptor signaling pathway, and Regulation of nucleotide-excision repair. Each is linked with ZNF764 in more than 16 cancer types. Because this analysis shows association rather than direction, both ZNF764-to-partner and partner-to-ZNF764 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of intracellular steroid hormone receptor signaling pathway grouped by ZNF764-low versus ZNF764-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF764→partner) and Y-score (partner→ZNF764) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.153	+1.055	.004	.002	3	17
BONE	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.215	+1.352	<.001	<.001	3	17
LUNG_SCLC	Regulation of nucleotide-excision repair →	+0.131	+0.783	<.001	<.001	3	16
SOFT_TISSUE	Metanephric proximal tubule development →	+0.241	+0.755	<.001	<.001	3	15
BONE	CAMP/PKA signal transduction →	+0.256	+1.299	<.001	<.001	3	15
BLOOD_Lymphoma	Negative regulation of autophagosome maturation →	+0.113	+0.878	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,658 associations by consensus.

Positive regulation of intracellular steroid hormone receptor signaling pathway by ZNF764 expression — BONE

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