ZNF76

Across TCGA pan-cancer cohorts, ZNF76 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ZNF76 data layer compared with 26 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZNF76 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated ZNF76 expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

UCEC, LSCC, and PDAC are the cancer types where ZNF76 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	All	1.000	0.869	.041	4	view →
LSCC	DFS	Quartile	II,III,IV	0.515	0.899	.026	3	view →
PDAC	DFS	Quartile	All	0.705	0.922	.024	3	view →
LUAD	OS	Quartile	All	0.918	1.000	.040	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ZNF76–UCEC (DFS)

Open the UCEC breakdown →