Across TCGA pan-cancer cohorts, ZNF75D Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ZNF75D data layer compared with 24 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ZNF75D Mutation is associated with better overall survival. In most high-consensus cancer types, elevated ZNF75D expression acts as an unfavorable survival marker, although some lineages such as UCEC and LUSC show a favorable association.

UCEC, CESC, and HNSC are the cancer types where ZNF75D Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	All	1.000	0.657	.010	16	view →
CESC	OS	Median	All	0.212	0.600	.016	4	view →
HNSC	OS	Median	III,IV	0.353	0.659	.022	4	view →
LUSC	DFS	Median	All	1.000	0.385	.046	1	view →
SKCM	DFS	Median	II,III,IV	0.542	0.245	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

Exploration

Same gene, other analysis: ZNF75D tumor-vs-normal RNA expression · all ZNF75D data types