ZNF75A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF75A mutation is significantly associated with the RNA expression of many other genes, with 2,171 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF75A-associated genes across cancer lineages are ASS1P6, RN7SKP42, and LINC01323. Each is linked with ZNF75A in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF75A-to-partner and partner-to-ZNF75A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ASS1P6 grouped by ZNF75A-low versus ZNF75A-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF75A→partner) and Y-score (partner→ZNF75A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAASS1P6 →+0.083+4.429.001.00632
BLCARN7SKP42 →+0.161+5.018<.001.00432
BLCALINC01323 →+0.249+5.213<.001.00132
LUADRNU6-565P →+0.385+4.481<.001.00932
LUADRPS7P9 →+0.108+4.631<.001.00832
UCECMIRLET7C →+0.291+2.221<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,171 associations by consensus.

ASS1P6 by ZNF75A expression — BLCA

Box plot of ASS1P6 in ZNF75A-low vs ZNF75A-high samples in BLCA.

Explore this box plot interactively →

Exploration