ZNF750

Across TCGA cell cohorts, ZNF750 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,495 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF750-associated GO terms across cancer lineages are Establishment or maintenance of epithelial cell apical/basal polarity, Negative regulation of RNA catabolic process, and miRNA processing. Each is linked with ZNF750 in more than 8 cancer types. Because this analysis shows association rather than direction, both ZNF750-to-partner and partner-to-ZNF750 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment or maintenance of epithelial cell apical/basal polarity grouped by ZNF750-low versus ZNF750-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF750→partner) and Y-score (partner→ZNF750) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Establishment or maintenance of epithelial cell apical/basal polarity →	+0.082	+0.840	<.001	.001	3	9
BONE	Negative regulation of RNA catabolic process →	+0.059	+0.252	.002	.009	3	9
SOFT_TISSUE	miRNA processing →	+0.084	+0.189	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Mycotoxin metabolic process →	-0.290	-2.178	<.001	<.001	3	8
UPPER_AERODIGESTIVE_TRACT	Aflatoxin metabolic process →	-0.290	-2.178	<.001	<.001	3	8
URINARY_TRACT	Neuroligin clustering involved in postsynaptic membrane assembly →	-1.328	-2.012	.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,495 associations by consensus.

Establishment or maintenance of epithelial cell apical/basal polarity by ZNF750 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →