Across TCGA patient cohorts, ZNF749 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,730 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF749-associated proteins across cancer lineages are TRIM28, PNKP, and PRMT1. Each is linked with ZNF749 in more than 7 cancer types. Because this analysis shows association rather than direction, both ZNF749-to-partner and partner-to-ZNF749 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF749→partner) and Y-score (partner→ZNF749) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TRIM28 →	+0.455	+0.673	<.001	<.001	3	8
BRCA	PNKP →	+0.374	+0.707	<.001	<.001	3	6
LUAD	PRMT1 →	+0.326	+0.526	<.001	<.001	3	6
GBM	ZNF787 →	+0.425	+0.509	<.001	<.001	3	6
GBM	SNRPD2 →	+0.278	+0.491	<.001	<.001	3	6
HNSC	XPO1 →	+0.202	+0.720	.003	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,730 associations by consensus.

Exploration

ZNF749 survival (RNA) · tumor vs normal (RNA) · all ZNF749 data types