Across TCGA cell cohorts, ZNF749 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,570 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF749-associated GO terms across cancer lineages are Cell adhesion mediated by integrin, Regulation of double-strand break repair, and Extracellular matrix organization. Each is linked with ZNF749 in more than 10 cancer types. Because this analysis shows association rather than direction, both ZNF749-to-partner and partner-to-ZNF749 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF749→partner) and Y-score (partner→ZNF749) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Cell adhesion mediated by integrin →	-0.196	-0.808	.005	.005	3	11
LUNG_SCLC	Regulation of double-strand break repair →	+0.068	+0.995	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Extracellular matrix organization →	-0.146	-0.733	<.001	.007	3	9
SOFT_TISSUE	Extracellular structure organization →	-0.144	-0.743	<.001	<.001	3	9
LUNG_NSCLC_LUSC	External encapsulating structure organization →	-0.144	-0.778	<.001	.005	3	9
SOFT_TISSUE	Positive regulation of monoatomic ion transmembrane transport →	-0.094	-0.543	.002	.003	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,570 associations by consensus.

Exploration

ZNF749 survival (RNA) · tumor vs normal (RNA) · all ZNF749 data types