ZNF746

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ZNF746 protein abundance is significantly associated with the RNA expression of many other genes, with 3,502 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF746-associated genes across cancer lineages are KIF6, BCAS1, and CCL13. Each is linked with ZNF746 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF746-to-partner and partner-to-ZNF746 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF746 versus KIF6 in GBM, with a Pearson correlation of -0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF746→partner) and Y-score (partner→ZNF746) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMKIF6 →-0.926-1.070<.001<.00132
GBMBCAS1 →-2.471-1.062<.001<.00132
LUADCCL13 →-1.203-0.322.006.00132
GBMSNORD3A →+0.746+0.737.004.00632
LSCCHDAC4 →+0.655+0.395<.001.00632
CCRCCCPA1 →+0.167+0.779.008.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,502 associations by consensus.

ZNF746 vs KIF6 — GBM

Per-sample scatter of ZNF746 vs KIF6 in GBM (Pearson r = -0.48).

Explore this scatter interactively →

Exploration