ZNF746

Across TCGA cell cohorts, ZNF746 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,812 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF746-associated GO terms across cancer lineages are Pre-mRNA catabolic process, Positive regulation of isotype switching to IgG isotypes, and Nucleic acid transport. Each is linked with ZNF746 in more than 14 cancer types. Because this analysis shows association rather than direction, both ZNF746-to-partner and partner-to-ZNF746 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pre-mRNA catabolic process grouped by ZNF746-low versus ZNF746-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF746→partner) and Y-score (partner→ZNF746) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pre-mRNA catabolic process →	+0.197	+0.626	<.001	<.001	3	15
BLOOD_Lymphoma	Positive regulation of isotype switching to IgG isotypes →	+0.146	+0.740	<.001	.002	3	14
PANCREAS	Nucleic acid transport →	+0.075	+0.638	.003	.002	3	14
PANCREAS	RNA transport →	+0.075	+0.638	.003	.002	3	14
PANCREAS	RNA export from nucleus →	+0.108	+0.830	<.001	<.001	3	14
PANCREAS	Nuclear export →	+0.103	+0.796	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,812 associations by consensus.

Pre-mRNA catabolic process by ZNF746 expression — BONE

Explore this box plot interactively →