ZNF740

Across TCGA patient cohorts, ZNF740 protein abundance is significantly associated with the RNA expression of many other genes, with 16,400 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible ZNF740-associated genes across cancer lineages are ATP5MC2, HNRNPA1, and SMARCC2. Each is linked with ZNF740 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF740-to-partner and partner-to-ZNF740 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZNF740 versus ATP5MC2 in LSCC, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF740→partner) and Y-score (partner→ZNF740) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ATP5MC2 →	+0.477	+0.245	<.001	<.001	3	5
UCEC	HNRNPA1 →	+0.636	+0.272	.002	.001	3	5
HNSC	SMARCC2 →	+0.648	+0.501	<.001	<.001	3	5
BRCA	EZH1 →	+0.543	+0.419	<.001	<.001	3	5
LSCC	MTERF2 →	+0.442	+0.261	<.001	<.001	3	5
HNSC	R3HDM2 →	+0.487	+0.410	.009	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,400 associations by consensus.

ZNF740 vs ATP5MC2 — LSCC

Explore this scatter interactively →