ZNF740

Across TCGA patient cohorts, ZNF740 mutation is significantly associated with the RNA expression of many other genes, with 916 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF740-associated genes across cancer lineages are LINC02641, CWC15, and TEX30. Each is linked with ZNF740 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF740-to-partner and partner-to-ZNF740 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02641 grouped by ZNF740-low versus ZNF740-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF740→partner) and Y-score (partner→ZNF740) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LINC02641 →	+0.246	+2.969	<.001	.001	3	2
UCEC	CWC15 →	+0.489	+3.361	.002	.005	3	1
UCEC	TEX30 →	+0.853	+3.467	<.001	.002	3	1
UCEC	GPATCH11 →	+0.620	+3.491	<.001	.002	3	1
UCEC	ARL14EP →	+0.481	+3.828	.005	<.001	3	1
UCEC	SAR1B →	+0.484	+3.265	.004	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 916 associations by consensus.

LINC02641 by ZNF740 expression — UCEC

Explore this box plot interactively →