ZNF740

Across TCGA cell cohorts, ZNF740 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,695 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF740-associated GO terms across cancer lineages are Positive regulation of double-strand break repair via homologous recombination, Positive regulation of DNA repair, and Host-mediated perturbation of viral transcription. Each is linked with ZNF740 in more than 18 cancer types. Because this analysis shows association rather than direction, both ZNF740-to-partner and partner-to-ZNF740 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair via homologous recombination grouped by ZNF740-low versus ZNF740-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF740→partner) and Y-score (partner→ZNF740) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of double-strand break repair via homologous recombination →	+0.112	+0.977	<.001	<.001	3	19
BONE	Positive regulation of DNA repair →	+0.073	+0.809	<.001	<.001	3	18
OVARY	Host-mediated perturbation of viral transcription →	+0.119	+0.770	<.001	<.001	3	17
OESOPHAGUS	Regulation of organelle assembly →	+0.045	+0.913	<.001	<.001	3	16
STOMACH	Host-mediated perturbation of viral process →	+0.102	+1.104	<.001	<.001	3	16
STOMACH	Regulation of DNA repair →	+0.076	+1.063	<.001	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,695 associations by consensus.

Positive regulation of double-strand break repair via homologous recombination by ZNF740 expression — STOMACH

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