Across TCGA patient cohorts, ZNF74 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,336 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZNF74-associated proteins across cancer lineages are RBM39, ADNP, and TCF20. Each is linked with ZNF74 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZNF74-to-partner and partner-to-ZNF74 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF74→partner) and Y-score (partner→ZNF74) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RBM39 →	+0.213	+0.635	<.001	<.001	3	7
GBM	ADNP →	+0.371	+0.740	<.001	<.001	3	7
BRCA	TCF20 →	+0.299	+0.381	<.001	<.001	3	7
HNSC	PHF14 →	+0.282	+0.688	<.001	<.001	3	7
GBM	ELAVL1 →	+0.276	+0.539	<.001	<.001	3	7
GBM	ILF2 →	+0.251	+0.649	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,336 associations by consensus.

Exploration

ZNF74 survival (RNA) · tumor vs normal (RNA) · all ZNF74 data types