ZNF738

Across TCGA patient cohorts, ZNF738 mutation is significantly associated with the RNA expression of many other genes, with 2,614 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF738-associated genes across cancer lineages are FAM74A6, RNA5SP410, and BNIP3. Each is linked with ZNF738 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF738-to-partner and partner-to-ZNF738 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM74A6 grouped by ZNF738-low versus ZNF738-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF738→partner) and Y-score (partner→ZNF738) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	FAM74A6 →	+0.009	+4.008	<.001	.001	3	3
UCEC	RNA5SP410 →	+0.679	+2.136	<.001	<.001	3	3
UCEC	BNIP3 →	+0.740	+1.807	<.001	<.001	3	3
LIHC	SNRPGP19 →	+0.175	+4.676	<.001	<.001	3	2
STAD	RNU6-271P →	+0.553	+4.691	.001	.003	3	2
UCEC	HMOX2 →	+0.346	+2.071	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,614 associations by consensus.

FAM74A6 by ZNF738 expression — LIHC

Explore this box plot interactively →