ZNF737

Across TCGA cell cohorts, ZNF737 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF737-associated genes across cancer lineages are OR7A10, SMR3B, and C1orf146. Each is linked with ZNF737 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF737-to-partner and partner-to-ZNF737 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR7A10 grouped by ZNF737-low versus ZNF737-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF737→partner) and Y-score (partner→ZNF737) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	OR7A10 →	+0.010	+4.781	<.001	.003	3	1
BREAST	SMR3B →	+0.052	+4.199	.003	.007	3	1
CNS	C1orf146 →	+0.036	+5.459	<.001	<.001	3	1
BLOOD_Leukemia	OR11H1 →	+0.063	+4.786	<.001	<.001	3	1
BLOOD_Leukemia	SLCO1C1 →	+0.076	+3.705	<.001	.007	3	1
BLOOD_Leukemia	LRTM1 →	+1.081	+4.234	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

OR7A10 by ZNF737 expression — BREAST

Explore this box plot interactively →