Across TCGA pan-cancer cohorts, ZNF736P4Y RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of ZNF736P4Y’s most consistent transcriptional readouts.
The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where ZNF736P4Y RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF736P4Y is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.
KIRP and KICH are the cancer types where ZNF736P4Y tumor–normal differential expression is most reproducible.