Across TCGA pan-cancer cohorts, ZNF736P10Y RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of ZNF736P10Y’s most consistent transcriptional readouts.
The strongest signal is observed in thyroid carcinoma (THCA), where ZNF736P10Y RNA is repressed in tumor relative to normal tissue. In most cancer types ZNF736P10Y is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.
THCA are the cancer types where ZNF736P10Y tumor–normal differential expression is most reproducible.