Across TCGA patient cohorts, ZNF735 mutation is significantly associated with the RNA expression of many other genes, with 4,058 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF735-associated genes across cancer lineages are RNU6-618P, CDKN3, and E2F1. Each is linked with ZNF735 in more than 3 cancer types. Because this analysis shows association rather than direction, both ZNF735-to-partner and partner-to-ZNF735 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF735→partner) and Y-score (partner→ZNF735) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIHC	RNU6-618P →	+0.553	+5.014	<.001	.002	3	4
UCEC	CDKN3 →	+0.619	+1.747	<.001	<.001	3	3
UCEC	E2F1 →	+0.747	+4.375	<.001	<.001	3	3
UCEC	NCAPG →	+0.671	+1.747	<.001	<.001	3	3
UCEC	FOXM1 →	+0.820	+2.214	<.001	<.001	3	3
UCEC	MASTL →	+0.395	+1.962	.006	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,058 associations by consensus.

Exploration

ZNF735 survival (RNA) · tumor vs normal (RNA) · all ZNF735 data types