Across TCGA patient cohorts, ZNF735 mutation is significantly associated with the total protein of many other genes, with 49 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF735-associated genes across cancer lineages are PDCD4, c-Met_pY1235, and Shc_pY317. Each is linked with ZNF735 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF735-to-partner and partner-to-ZNF735 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF735→partner) and Y-score (partner→ZNF735) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PDCD4 →	-0.502	-2.321	<.001	.005	3	3
LUSC	c-Met_pY1235 →	+0.074	+2.825	.023	.033	3	3
UCEC	Shc_pY317 →	-0.150	-1.415	.001	.010	3	3
UCEC	VHL →	-0.796	-2.392	<.001	<.001	3	3
UCEC	ASNS →	+0.460	+1.925	<.001	.004	3	3
LUAD	p27_pT198 →	+0.140	+3.016	.034	.018	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 49 associations by consensus.

Exploration

ZNF735 survival (RNA) · tumor vs normal (RNA) · all ZNF735 data types