Across TCGA patient cohorts, ZNF730 mutation is significantly associated with the total protein of many other genes, with 42 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF730-associated genes across cancer lineages are C-Raf, 14-3-3_beta, and A-Raf_pS299. Each is linked with ZNF730 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF730-to-partner and partner-to-ZNF730 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF730→partner) and Y-score (partner→ZNF730) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	C-Raf →	+0.227	+2.841	.004	.033	3	3
UCEC	14-3-3_beta →	-0.078	-1.673	.017	.040	3	2
UCEC	A-Raf_pS299 →	-0.119	-1.716	.002	.003	3	2
UCEC	FOXO3a_pS318_S321 →	-0.105	-1.755	.009	.013	3	2
UCEC	GAPDH →	+0.344	+1.874	.048	.049	3	2
UCEC	Lck →	+0.174	+1.700	.007	.042	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 42 associations by consensus.

Exploration

ZNF730 survival (RNA) · tumor vs normal (RNA) · all ZNF730 data types