Across TCGA cell cohorts, ZNF730 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,202 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF730-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of stem cell population maintenance, and Regulation of transcription initiation by RNA polymerase II. Each is linked with ZNF730 in more than 11 cancer types. Because this analysis shows association rather than direction, both ZNF730-to-partner and partner-to-ZNF730 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF730→partner) and Y-score (partner→ZNF730) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA metabolic process →	+0.081	+1.289	<.001	<.001	3	12
BLOOD_Leukemia	Regulation of stem cell population maintenance →	+0.055	+1.119	<.001	<.001	3	10
LUNG_SCLC	Regulation of transcription initiation by RNA polymerase II →	+0.053	+1.287	.006	.001	3	10
SOFT_TISSUE	Regulation of double-strand break repair →	+0.101	+1.386	<.001	<.001	3	10
SOFT_TISSUE	Positive regulation of DNA repair →	+0.099	+1.313	<.001	<.001	3	10
SOFT_TISSUE	Regulation of DNA repair →	+0.046	+0.917	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,202 associations by consensus.

Exploration

ZNF730 survival (RNA) · tumor vs normal (RNA) · all ZNF730 data types