Across TCGA cell cohorts, ZNF730 mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF730-associated genes across cancer lineages are PBOV1, ARGFX, and ASPN. Each is linked with ZNF730 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF730-to-partner and partner-to-ZNF730 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF730→partner) and Y-score (partner→ZNF730) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	PBOV1 →	+0.011	+4.196	.001	.002	3	1
OVARY	ARGFX →	+0.035	+5.196	<.001	.005	3	1
LARGE_INTESTINE	ASPN →	+0.032	+3.841	.007	<.001	3	1
LARGE_INTESTINE	GTF2B →	+0.440	+3.215	.002	.009	3	1
LARGE_INTESTINE	MINAR2 →	+0.024	+2.560	.006	.008	3	1
LARGE_INTESTINE	DAZ4 →	+0.109	+2.977	.008	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

Exploration

ZNF730 survival (RNA) · tumor vs normal (RNA) · all ZNF730 data types