Across TCGA pan-cancer cohorts, ZNF729 Mutation is linked to patient survival in 2 of 34 cancer types, making it a survival-associated ZNF729 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher ZNF729 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ZNF729 expression acts as an unfavorable survival marker.

CESC and OV are the cancer types where ZNF729 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	III,IV	0.091	0.755	<.001	24	view →
OV	DFS	Median	All	0.261	0.541	.017	18	view →

Pink = unfavorable, green = favorable. Showing the 2 strongest of 2 lineages.

Exploration

Same gene, other analysis: ZNF729 tumor-vs-normal RNA expression · all ZNF729 data types