Across TCGA patient cohorts, ZNF727 mutation is significantly associated with the RNA expression of many other genes, with 3,188 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF727-associated genes across cancer lineages are LINC01097, MIR6870, and CCL3. Each is linked with ZNF727 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF727-to-partner and partner-to-ZNF727 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF727→partner) and Y-score (partner→ZNF727) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01097 →	+0.059	+4.613	<.001	.001	3	2
UCEC	MIR6870 →	+0.276	+1.659	<.001	.009	3	2
UCEC	CCL3 →	+0.645	+1.669	<.001	.001	3	2
CESC	RN7SL166P →	+0.154	+4.063	.009	.002	3	2
BRCA	RNVU1-23 →	+0.191	+4.527	<.001	.007	3	2
BRCA	MIR4533 →	+0.292	+4.683	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,188 associations by consensus.

Exploration

ZNF727 survival (RNA) · tumor vs normal (RNA) · all ZNF727 data types