Across TCGA patient cohorts, ZNF727 mutation is significantly associated with the total protein of many other genes, with 32 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF727-associated genes across cancer lineages are eIF4E, INPP4B, and p27_pT198. Each is linked with ZNF727 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF727-to-partner and partner-to-ZNF727 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF727→partner) and Y-score (partner→ZNF727) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.185	+2.263	.007	<.001	3	2
UCEC	INPP4B →	-0.241	-2.115	.023	.016	3	2
UCEC	p27_pT198 →	+0.088	+2.321	.012	.033	3	2
UCEC	ASNS →	+0.357	+1.807	.002	.024	3	2
UCEC	ATM →	-0.443	-1.765	.002	.013	3	2
UCEC	14-3-3_beta →	-0.088	-1.379	.007	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 32 associations by consensus.

Exploration

ZNF727 survival (RNA) · tumor vs normal (RNA) · all ZNF727 data types