Across TCGA cell cohorts, ZNF727 mutation is significantly associated with the RNA expression of many other genes, with 30 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZNF727-associated genes across cancer lineages are OR4K1, C8orf89, and OR4X2. Each is linked with ZNF727 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF727-to-partner and partner-to-ZNF727 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF727→partner) and Y-score (partner→ZNF727) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR4K1 →	+0.409	+4.969	<.001	.003	3	2
LIVER	C8orf89 →	+0.067	+3.977	<.001	.006	3	1
SOFT_TISSUE	OR4X2 →	+0.032	+5.369	<.001	.004	3	1
SOFT_TISSUE	GSTA5 →	+0.021	+4.930	.001	.008	3	1
SOFT_TISSUE	KRTAP20-2 →	+0.097	+5.369	<.001	.004	3	1
SKIN	EDDM3B →	+0.032	+5.415	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 30 associations by consensus.

Exploration

ZNF727 survival (RNA) · tumor vs normal (RNA) · all ZNF727 data types