Across TCGA patient cohorts, ZNF726 mutation is significantly associated with the RNA expression of many other genes, with 1,008 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF726-associated genes across cancer lineages are RAB11AP1, TBC1D3P1-DHX40P1, and RN7SL134P. Each is linked with ZNF726 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF726-to-partner and partner-to-ZNF726 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF726→partner) and Y-score (partner→ZNF726) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	RAB11AP1 →	+0.144	+5.039	.001	.008	3	2
READ	TBC1D3P1-DHX40P1 →	+0.284	+5.925	<.001	.002	3	2
UCEC	RN7SL134P →	+0.105	+2.184	.001	.004	3	2
UCEC	RNU6ATAC29P →	+0.247	+2.064	.005	.003	3	2
UCEC	RNA5SP222 →	+0.206	+3.214	<.001	.004	3	2
UCEC	RNA5SP497 →	+0.346	+2.601	.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,008 associations by consensus.

Exploration

ZNF726 survival (RNA) · tumor vs normal (RNA) · all ZNF726 data types