Across TCGA patient cohorts, ZNF726 mutation is significantly associated with the total protein of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF726-associated genes across cancer lineages are ASNS, 14-3-3_beta, and EGFR_pY1068. Each is linked with ZNF726 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF726-to-partner and partner-to-ZNF726 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF726→partner) and Y-score (partner→ZNF726) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ASNS →	+0.420	+3.000	.004	.001	3	2
UCEC	14-3-3_beta →	-0.096	-2.301	.020	.034	3	1
UCEC	EGFR_pY1068 →	-0.264	-3.321	.010	.010	3	1
UCEC	ERK2 →	+0.244	+2.321	.002	.006	3	1
UCEC	FOXO3a →	-0.132	-3.308	.001	.009	3	1
UCEC	HER3 →	-0.248	-3.311	.028	.010	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

Exploration

ZNF726 survival (RNA) · tumor vs normal (RNA) · all ZNF726 data types