Across TCGA patient cohorts, ZNF724 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF724-associated genes across cancer lineages are MEK1, TSC1, and Caspase-7-cleavedD198. Each is linked with ZNF724 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF724-to-partner and partner-to-ZNF724 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF724→partner) and Y-score (partner→ZNF724) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MEK1 →	+0.375	+2.087	.003	.005	3	3
UCEC	TSC1 →	-0.147	-2.420	.014	.018	3	2
UCEC	Caspase-7-cleavedD198 →	+0.930	+3.019	<.001	<.001	3	2
UCEC	4E-BP1 →	+0.244	+2.459	.010	.018	3	2
UCEC	EGFR_pY1068 →	-0.240	-2.000	.006	.003	3	1
UCEC	GATA6 →	-0.112	-1.700	.041	.042	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration

ZNF724 survival (RNA) · tumor vs normal (RNA) · all ZNF724 data types