Across TCGA cell cohorts, ZNF724 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZNF724-associated genes across cancer lineages are PRT062607, AZD5991, and 123829. Each is linked with ZNF724 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF724-to-partner and partner-to-ZNF724 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF724→partner) and Y-score (partner→ZNF724) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PRT062607 →	+0.650	+2.777	.009	.030	3	1
LARGE_INTESTINE	AZD5991 →	+0.927	+2.649	.015	.046	3	1
LARGE_INTESTINE	123829 →	+0.718	+2.649	.012	.046	3	1
LARGE_INTESTINE	KRAS (G12C) Inhibitor-12 →	+0.598	+2.646	.016	.047	3	1
LARGE_INTESTINE	AZD5438 →	+0.525	+2.777	.033	.038	2	1
LARGE_INTESTINE	Teniposide →	+0.610	+2.649	.021	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

Exploration

ZNF724 survival (RNA) · tumor vs normal (RNA) · all ZNF724 data types