ZNF723

Across TCGA patient cohorts, ZNF723 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,644 significant associations in total. STAD shows the largest number of these associations.

The most reproducible ZNF723-associated GO terms across cancer lineages are Telomere maintenance via telomere lengthening, Protein sumoylation, and Positive regulation of cell cycle phase transition. Each is linked with ZNF723 in more than 20 cancer types. Because this analysis shows association rather than direction, both ZNF723-to-partner and partner-to-ZNF723 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomere maintenance via telomere lengthening grouped by ZNF723-low versus ZNF723-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF723→partner) and Y-score (partner→ZNF723) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Telomere maintenance via telomere lengthening →	+0.061	+0.147	<.001	<.001	3	21
STAD	Protein sumoylation →	+0.095	+0.188	<.001	<.001	3	21
ESCA	Positive regulation of cell cycle phase transition →	+0.086	+0.225	<.001	<.001	3	20
STAD	Transcription initiation at RNA polymerase II promoter →	+0.062	+0.169	<.001	<.001	3	20
ESCA	Nucleus organization →	+0.065	+0.172	<.001	<.001	3	20
STAD	Negative regulation of DNA metabolic process →	+0.052	+0.143	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,644 associations by consensus.

Telomere maintenance via telomere lengthening by ZNF723 expression — STAD

Explore this box plot interactively →