Across TCGA patient cohorts, ZNF721 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,004 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZNF721-associated proteins across cancer lineages are HDGFL2, HTT, and CTBP1. Each is linked with ZNF721 in more than 4 cancer types. Because this analysis shows association rather than direction, both ZNF721-to-partner and partner-to-ZNF721 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF721→partner) and Y-score (partner→ZNF721) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	HDGFL2 →	+0.396	+0.512	<.001	.001	3	5
BRCA	HTT →	+0.220	+0.622	.001	<.001	3	5
PDAC	CTBP1 →	+0.491	+0.414	<.001	<.001	3	5
PDAC	EEF2_T57 →	-0.636	-0.333	<.001	.001	3	5
UCEC	PPP1R8 →	+0.181	+0.518	<.001	.005	3	4
GBM	PRCC →	+0.306	+0.448	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,004 associations by consensus.

Exploration

ZNF721 survival (RNA) · tumor vs normal (RNA) · all ZNF721 data types