ZNF718

Across TCGA patient cohorts, ZNF718 mutation is significantly associated with the RNA expression of many other genes, with 1,621 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF718-associated genes across cancer lineages are FCGR1A, NCAPD3, and SKA1. Each is linked with ZNF718 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF718-to-partner and partner-to-ZNF718 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FCGR1A grouped by ZNF718-low versus ZNF718-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF718→partner) and Y-score (partner→ZNF718) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FCGR1A →	+0.539	+2.194	.001	.001	3	2
UCEC	NCAPD3 →	+0.528	+1.773	.001	.008	3	2
UCEC	SKA1 →	+0.578	+1.885	.001	.001	3	2
UCEC	CXCL13 →	+2.031	+2.201	<.001	<.001	3	2
UCEC	C1QC →	+0.763	+2.700	.005	.005	3	2
UCEC	LAPTM5 →	+0.624	+2.332	.004	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,621 associations by consensus.

FCGR1A by ZNF718 expression — UCEC

Explore this box plot interactively →