Across TCGA patient cohorts, ZNF717 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF717-associated genes across cancer lineages are EGFR_pY1068, eIF4E, and A-Raf_pS299. Each is linked with ZNF717 in more than 1 cancer types. Because this analysis shows association rather than direction, both ZNF717-to-partner and partner-to-ZNF717 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF717→partner) and Y-score (partner→ZNF717) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.242	-2.201	.004	<.001	3	1
UCEC	eIF4E →	+0.209	+2.201	.003	<.001	3	1
UCEC	A-Raf_pS299 →	-0.099	-2.321	.013	.005	3	1
UCEC	FOXO3a_pS318_S321 →	-0.088	-1.668	.035	.021	3	1
UCEC	JNK_pT183_Y185 →	-0.158	-1.861	.005	.002	3	1
UCEC	JNK2 →	+0.205	+1.321	.002	.029	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

Exploration

ZNF717 survival (RNA) · tumor vs normal (RNA) · all ZNF717 data types