ZNF714

Across TCGA patient cohorts, ZNF714 mutation is significantly associated with the RNA expression of many other genes, with 3,831 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF714-associated genes across cancer lineages are ZMYND19, TRUB2, and SCIN. Each is linked with ZNF714 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF714-to-partner and partner-to-ZNF714 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZMYND19 grouped by ZNF714-low versus ZNF714-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF714→partner) and Y-score (partner→ZNF714) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZMYND19 →	+0.610	+3.491	<.001	<.001	3	3
UCEC	TRUB2 →	+0.441	+3.502	<.001	<.001	3	3
UCEC	SCIN →	-0.553	-3.207	.002	<.001	3	3
UCEC	CCT7 →	+0.444	+2.343	<.001	<.001	3	3
UCEC	RNU1-100P →	+0.242	+1.670	.004	.007	3	3
UCEC	LINC01670 →	+0.072	+2.017	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,831 associations by consensus.

ZMYND19 by ZNF714 expression — UCEC

Explore this box plot interactively →