ZNF714

Across TCGA patient cohorts, ZNF714 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZNF714-associated genes across cancer lineages are FoxM1, STAT3_pY705, and Caspase-7-cleavedD198. Each is linked with ZNF714 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZNF714-to-partner and partner-to-ZNF714 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by ZNF714-low versus ZNF714-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF714→partner) and Y-score (partner→ZNF714) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.246	+1.906	.018	.016	3	3
UCEC	STAT3_pY705 →	-0.404	-1.906	<.001	.016	3	3
UCEC	Caspase-7-cleavedD198 →	+0.636	+2.479	.007	.010	3	3
UCEC	PKC-delta_pS664 →	-0.114	-3.321	.018	.009	3	2
UCEC	Rictor_pT1135 →	-0.090	-1.906	.028	.016	3	2
UCEC	Shc_pY317 →	-0.196	-2.115	.001	.017	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

FoxM1 by ZNF714 expression — UCEC

Explore this box plot interactively →