ZNF714

Across TCGA cell cohorts, ZNF714 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,284 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ZNF714-associated GO terms across cancer lineages are Constitutive heterochromatin formation, Regulation of sister chromatid segregation, and Regulation of DNA repair. Each is linked with ZNF714 in more than 13 cancer types. Because this analysis shows association rather than direction, both ZNF714-to-partner and partner-to-ZNF714 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Constitutive heterochromatin formation grouped by ZNF714-low versus ZNF714-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZNF714→partner) and Y-score (partner→ZNF714) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Constitutive heterochromatin formation →	+0.100	+1.400	<.001	<.001	3	14
URINARY_TRACT	Regulation of sister chromatid segregation →	+0.078	+1.437	<.001	<.001	3	13
SOFT_TISSUE	Regulation of DNA repair →	+0.072	+1.465	<.001	<.001	3	12
SOFT_TISSUE	Regulation of centrosome duplication →	+0.073	+1.337	.002	<.001	3	12
BLOOD_Lymphoma	Mitotic nuclear division →	+0.091	+1.587	<.001	<.001	3	12
URINARY_TRACT	Positive regulation of cell cycle →	+0.058	+1.459	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,284 associations by consensus.

Constitutive heterochromatin formation by ZNF714 expression — BLOOD_Lymphoma

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